Ovarian dysfunction with moderate-dose intravenous cyclophosphamide (modified NIH regimen) and mycophenolate mofetil in young adults with severe lupus: a prospective cohort study

Ovarian dysfunction with moderate-dose intravenous cyclophosphamide (modified NIH regimen) and mycophenolate mofetil in young adults with severe lupus: a prospective cohort study

Abstract Background Ovarian toxicity is a dreaded complication of cyclophosphamide (CYC). With the use of lower cumulative doses of intravenous CYC (modified NIH regimens) and availability of better markers of ovarian toxicity, the incidence of ovarian dysfunction needs reassessment. Lupus disease a...

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Bibliographic Details
Main Authors: Shefali Khanna Sharma, Siddharth Jain, Pooja Bahl, Pragna Potturi, Manish Rathi, Shankar Naidu, Naresh Sachdeva, Varun Dhir, Sanjay Jain
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Arthritis Research & Therapy
Subjects:
Cyclophosphamide
Gonadotoxicity
Systemic lupus erythematosus
Mycophenolate mofetil
Ovarian dysfunction
Online Access:http://link.springer.com/article/10.1186/s13075-020-02292-y

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http://link.springer.com/article/10.1186/s13075-020-02292-y

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