Mealtime, temporal, and daily variability of the human urinary and plasma metabolomes in a tightly controlled environment.

While metabolomics has tremendous potential for diagnostic biomarker and therapeutic target discovery, its utility may be diminished by the variability that occurs due to environmental exposures including diet and the influences of the human circadian rhythm. For successful translation of metabolomi...

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Bibliographic Details
Main Authors: Kyoungmi Kim, Christine Mall, Sandra L Taylor, Stacie Hitchcock, Chen Zhang, Hiromi I Wettersten, A Daniel Jones, Arlene Chapman, Robert H Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3901684?pdf=render