MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma.

MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma.

No reliable predictors of susceptibility to gemcitabine chemotherapy exist in pancreatic ductal adenocarcinoma (PDAC). MicroRNAs (miR) are epigenetic gene regulators with tumorsuppressive or oncogenic roles in various carcinomas. This study assesses chemoresistant PDAC for its specific miR expressio...

Full description

Bibliographic Details
Main Authors: Sameer A Dhayat, Wolf Arif Mardin, Jochen Seggewiß, Anda Jana Ströse, Christiane Matuszcak, Richard Hummel, Norbert Senninger, Sören Torge Mees, Jörg Haier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4659591?pdf=render

Internet

http://europepmc.org/articles/PMC4659591?pdf=render

Similar Items