scHiCTools: A computational toolbox for analyzing single-cell Hi-C data.

Single-cell Hi-C (scHi-C) sequencing technologies allow us to investigate three-dimensional chromatin organization at the single-cell level. However, we still need computational tools to deal with the sparsity of the contact maps from single cells and embed single cells in a lower-dimensional Euclid...

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Bibliographic Details
Main Authors: Xinjun Li, Fan Feng, Hongxi Pu, Wai Yan Leung, Jie Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-05-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008978