PIWI expression and function in cancer

PIWI proteins, a subclade of the Argonaute family proteins, are expressed predominantly in the germline and bind to PIWI-interacting RNAs (piRNAs), which are 25-31 nucleotides in length. The PIWI/piRNA pathway plays critical roles in germline development by regulating transposons and other targets t...

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Bibliographic Details
Main Authors: Ryusuke eSuzuki, Shozo eHonda, Yohei eKirino
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Genetics
Subjects:
AGO
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00204/full