Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

Cosplicing network analysis of mammalian brain RNA-Seq data utilizing WGCNA and Mantel correlations

Across species and tissues and especially in the mammalian brain, production of gene isoforms is widespread. While gene expression coordination has been previously described as a scale-free coexpression network, the properties of transcriptome-wide isoform production coordination have been less stud...

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Bibliographic Details
Main Authors: Ovidiu Dan Iancu, Alexandre eColville, Denesa eOberbeck, Priscila eDarakjian, Shannon K McWeeney, Robert eHitzemann
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Genetics
Subjects:
Alternative Splicing
scale free networks
Gene coexpression
gene cosplicing
brain transcriptome
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00174/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00174/full

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