Targeting insulin-like growth factor axis in hepatocellular carcinoma

<p>Abstract</p> <p>The insulin-like growth factor (IGF) axis contains ligands, receptors, substrates, and ligand binding proteins. The essential role of IGF axis in hepatocellular carcinoma (HCC) has been illustrated in HCC cell lines and in animal xenograft models. Preclinical evi...

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Bibliographic Details
Main Authors: Wu Jennifer, Zhu Andrew X
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/4/1/30