Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A Streptococcus To Initiate Autophagy during Infection

Integrin α5β1, as a Receptor of Fibronectin, Binds the FbaA Protein of Group A Streptococcus To Initiate Autophagy during Infection

Autophagy is generally considered a strategy used by the innate immune system to eliminate invasive pathogens through capturing and transferring them to lysosomes. Currently, researchers pay more attention to how virulence factors secreted by GAS regulate the autophagic process. Here, we provide the...

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Bibliographic Details
Main Authors: Jiachao Wang, Meiqi Meng, Miao Li, Xiaofei Guan, Jianguo Liu, Xue Gao, Qingqing Sun, Jinquan Li, Cuiqing Ma, Lin Wei
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
autophagy
group a streptococcus
fbaa protein
integrin α5β1
fibronectin
Online Access:https://doi.org/10.1128/mBio.00771-20

Internet

https://doi.org/10.1128/mBio.00771-20

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