A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth

A Novel Long-Acting Glucagon-Like Peptide-1 Agonist with Improved Efficacy in Insulin Secretion and β-Cell Growth

BackgroundGlucagon-like peptide-1 (GLP-1) is an incretin hormone produced by cleavage of proglucagon in intestinal L-cells. In the pancreas, GLP-1 stimulates post-prandial insulin secretion, promotes insulin biosynthesis, and improves insulin sensitivity. Because of its insulinotropic activity, GLP-...

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Bibliographic Details
Main Authors: Hee Young Kim, Jong-Ik Hwang, Mi Jin Moon, Jae Young Seong
Format: Article
Language:English
Published: Academya Publishing Co. 2014-09-01
Series:Endocrinology and Metabolism
Subjects:
Glucagon-like peptide 1
Exenatide
xGLP-E4
Analog
Diabetes
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-320.pdf

Internet

http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-320.pdf

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