A distinct microRNA expression profile is associated with α[11C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers resected from patients with tuberous sclerosis complex

A distinct microRNA expression profile is associated with α[11C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers resected from patients with tuberous sclerosis complex

Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in various organs and arises due to mutations in the TSC1 or TSC2 genes. TSC mutations lead to a range of neurological manifestations including epilepsy, cognitive impairment, autism spectrum disorders (ASD), and brain lesion...

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Bibliographic Details
Main Authors: Shruti Bagla, Daniela Cukovic, Eishi Asano, Sandeep Sood, Aimee Luat, Harry T. Chugani, Diane C. Chugani, Alan A. Dombkowski
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Neurobiology of Disease
Subjects:
Tuberous sclerosis complex
Epilepsy
Seizure
microRNA
Tryptophan
α[11C]-methyl-L-tryptophan
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302231

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http://www.sciencedirect.com/science/article/pii/S0969996117302231

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