RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

The innate immune system senses pathogens by pattern recognition receptors in different cell compartments. In the endosome, bacteria are generally recognized by TLRs; facultative intracellular bacteria such as Listeria, however, can escape the endosome. Once in the cytosol, they become accessible to...

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Bibliographic Details
Main Authors: Cristina Amparo Hagmann, Anna Maria Herzner, Zeinab Abdullah, Thomas Zillinger, Christopher Jakobs, Christine Schuberth, Christoph Coch, Paul G Higgins, Hilmar Wisplinghoff, Winfried Barchet, Veit Hornung, Gunther Hartmann, Martin Schlee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3639904?pdf=render

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http://europepmc.org/articles/PMC3639904?pdf=render

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