RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.
The innate immune system senses pathogens by pattern recognition receptors in different cell compartments. In the endosome, bacteria are generally recognized by TLRs; facultative intracellular bacteria such as Listeria, however, can escape the endosome. Once in the cytosol, they become accessible to...
Main Authors: | Cristina Amparo Hagmann, Anna Maria Herzner, Zeinab Abdullah, Thomas Zillinger, Christopher Jakobs, Christine Schuberth, Christoph Coch, Paul G Higgins, Hilmar Wisplinghoff, Winfried Barchet, Veit Hornung, Gunther Hartmann, Martin Schlee |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3639904?pdf=render |
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