Research Progress of Secreted Frizzled-related Proteins in Female Malignant Tumor

The classical Wnt signaling pathway receptor inhibitors are composed of secreted frizzled-related proteins (SFRPs) and the Dickkopf family (Dkk). SFRPs inhibit wnt/β-catenin signaling by sequestering Wnt from the active receptor complexes. In tumor progression, epigenetic silencing of SFRPs promoter...

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Bibliographic Details
Main Authors: ZHANG Lixuan, LIU Chaoqi, LI Zhiying
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2020-03-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2020.19.0972.htm