Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ.

Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ.

Signaling regulated by NFκB and related transcription factors is centrally important to many inflammatory and autoimmune diseases, cancer, and stress responses. The kinase that directly regulates the canonical NFκB transcriptional pathway, Inhibitor of κB kinase β (IKKβ), undergoes activation by Ser...

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Bibliographic Details
Main Authors: April N Meyer, Kristine A Drafahl, Christopher W McAndrew, Jennifer E Gilda, Leandro H Gallo, Martin Haas, Laurence M Brill, Daniel J Donoghue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24386391/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24386391/pdf/?tool=EBI

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