miR-145-5p Suppresses Tumor Cell Migration, Invasion and Epithelial to Mesenchymal Transition by Regulating the Sp1/NF-κB Signaling Pathway in Esophageal Squamous Cell Carcinoma

miR-145-5p Suppresses Tumor Cell Migration, Invasion and Epithelial to Mesenchymal Transition by Regulating the Sp1/NF-κB Signaling Pathway in Esophageal Squamous Cell Carcinoma

MicroRNAs (miRNAs) play important roles in the progression of human cancer. Although previous reports have shown that miR-145-5p is down-regulated in esophageal squamous cell carcinoma (ESCC), the roles and mechanisms of down-regulation of miR-145-5p in ESCC are still largely unknown. Using microRNA...

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Bibliographic Details
Main Authors: Li-Li Mei, Wen-Jun Wang, Yun-Tan Qiu, Xiu-Feng Xie, Jie Bai, Zhi-Zhou Shi
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:International Journal of Molecular Sciences
Subjects:
miR-145-5p
esophageal squamous cell carcinoma (ESCC)
Sp1
NF-κB
epithelial to mesenchymal transition (EMT)
Online Access:https://www.mdpi.com/1422-0067/18/9/1833

Internet

https://www.mdpi.com/1422-0067/18/9/1833

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