A simvastatin-releasing scaffold with periodontal ligament stem cell sheets for periodontal regeneration

Simvastatin (SIM) has been documented to induce the osteogenic differentiation of periodontal ligament stem cells (PDLSCs). To establish an efficient release system for periodontal regeneration, a polycaprolactone (PCL) membrane scaffold containing SIM was electrospun and evaluated. The obtained PCL...

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Bibliographic Details
Main Authors: Bingjiao Zhao, Jing Chen, Liru Zhao, Jiajia Deng, Qiang Li
Format: Article
Language:English
Published: SAGE Publishing 2020-05-01
Series:Journal of Applied Biomaterials & Functional Materials
Online Access:https://doi.org/10.1177/2280800019900094