An in silico modeling approach to understanding the dynamics of sarcoidosis.

BACKGROUND: Sarcoidosis is a polygenic disease with diverse phenotypic presentations characterized by an abnormal antigen-mediated Th1 type immune response. At present, progress towards understanding sarcoidosis disease mechanisms and the development of novel treatments is limited by constraints att...

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Bibliographic Details
Main Authors: Baltazar D Aguda, Clay B Marsh, Michael Thacker, Elliott D Crouser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3103504?pdf=render