Evidence for a third genetic locus causing familial hypercholesterolemia: a non-LDLR, non-APOB kindred1

Evidence for a third genetic locus causing familial hypercholesterolemia: a non-LDLR, non-APOB kindred1

Monogenically inherited hypercholesterolemia is most commonly caused by mutations at the low density lipoprotein receptor (LDLR) locus causing familial hypercholesterolemia (FH) or at the apolipoprotein B (APOB) locus causing the disorder familial defective apoB (FDB). Probands from 47 kindreds with...

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Bibliographic Details
Main Authors: L. Haddad, I.N.M. Day, S. Hunt, R.R. Williams, S.E. Humphries, P.N. Hopkins
Format: Article
Language:English
Published: Elsevier 1999-06-01
Series:Journal of Lipid Research
Subjects:
familial hypercholesterolemia
LDLR gene
APOB gene
microsatellites
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033515X

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http://www.sciencedirect.com/science/article/pii/S002222752033515X

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