Crystal structure of methyl (S)-2-{(R)-4-[(tert-butoxycarbonyl)amino]-3-oxo-1,2-thiazolidin-2-yl}-3-methylbutanoate: a chemical model for oxidized protein tyrosine phosphatase 1B (PTP1B)

Crystal structure of methyl (S)-2-{(R)-4-[(tert-butoxycarbonyl)amino]-3-oxo-1,2-thiazolidin-2-yl}-3-methylbutanoate: a chemical model for oxidized protein tyrosine phosphatase 1B (PTP1B)

The asymmetric unit of the title compound, C14H24N2O5S, contains two independent molecules (A and B). In each molecule, the isothiazolidin-3-one ring adopts an envelope conformation with the methylene C atom as the flap. In the crystal, the A molecules are linked to one another by N—H...O hydrogen b...

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Bibliographic Details
Main Authors: Kasi Viswanatharaju Ruddraraju, Roman Hillebrand, Charles L. Barnes, Kent S. Gates
Format: Article
Language:English
Published: International Union of Crystallography 2015-07-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
crystal structure
isothiazolidine-3-one derivative
oxidized PTP1B
sulfenyl amide
hydrogen bonding
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989015010051

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http://scripts.iucr.org/cgi-bin/paper?S2056989015010051

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