Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice.

Modifications of adjuvants that induce cell-mediated over antibody-mediated immunity is desired for development of vaccines. Nanocapsules have been found to be viable adjuvants and are amenable to engineering for desired immune responses. We previously showed that natural nanocapsules called vaults...

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Bibliographic Details
Main Authors: Upendra K Kar, Janina Jiang, Cheryl I Champion, Sahar Salehi, Minu Srivastava, Sherven Sharma, Shahrooz Rabizadeh, Kayvan Niazi, Valerie Kickhoefer, Leonard H Rome, Kathleen A Kelly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3394761?pdf=render