Presynaptic Release-Regulating mGlu1 Receptors in Central Nervous System

Group I metabotropic glutamate (mGlu) receptors consists of mGlu1 and mGlu5 receptor subtypes. These receptors are widely distributed in the central nervous system (CNS), where they preferentially mediate facilitatory signalling in neurones and glial cells, mainly by favouring phospholipase (PLC) tr...

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Bibliographic Details
Main Author: Anna Maria Pittaluga
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00295/full