In utero hematopoietic cell transplantation: Induction of donor specific immune tolerance and postnatal transplants

In utero hematopoietic cell transplantation (IUHCT) is a nonmyeloablative nonimmunosuppressive transplant approach that allows for donor cell engraftment across immunologic barriers. Successful engraftment is associated with donor-specific tolerance. IUHCT has the potential to treat a large number o...

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Bibliographic Details
Main Author: William H. Peranteau
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00251/full