Evaluation of toxicity and anti-osteoporosis effect in rats treated with the flavonoids of Psoraleae Fructus

Evaluation of toxicity and anti-osteoporosis effect in rats treated with the flavonoids of Psoraleae Fructus

The dried fruits of Psoralea corylifolia Linn are called Psoraleae Fructus (FP), widely used in postmenopausal osteoporosis treatment. However, FP-induced hepatotoxicity has been reported, which might be caused by bakuchiol, psoralen and isopsoralen. In our study, bakuchiol, psoralen and isopsoralen...

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Bibliographic Details
Main Authors: Bojia Liu, Xinxin Liu, Qing Ning, Rongling Zhong, Zhi Xia, Jiayan Li, Jie Song, Yingjie Wei
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Functional Foods
Subjects:
Osteoporosis
Psoraleae Fructus
Flavonoids
Zebrafish
OPG/RANKL
Runx2
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464620304862

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http://www.sciencedirect.com/science/article/pii/S1756464620304862

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