BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury

BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury

Abstract Background Radiation-induced gastrointestinal syndrome (RIGS) results from the acute loss of intestinal stem cells (ISC), impaired epithelial regeneration, and subsequent loss of the mucosal barrier, resulting in electrolyte imbalance, diarrhea, weight loss, sepsis, and mortality. The high...

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Bibliographic Details
Main Authors: Payel Bhanja, Andrew Norris, Pooja Gupta-Saraf, Andrew Hoover, Subhrajit Saha
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Stem Cell Research & Therapy
Subjects:
Intestinal stem cell
RIGS
Abdominal radiation
Radiotherapy
Tumor
Online Access:http://link.springer.com/article/10.1186/s13287-017-0763-3

Internet

http://link.springer.com/article/10.1186/s13287-017-0763-3

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