Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway

Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway

Dioscin, a natural product, has activity against glioblastoma multiforme, lung cancer and colon cancer. In this study, the effects of dioscin against human cervical carcinoma HeLa and SiHa cells were further confirmed, and the possible mechanism(s) were investigated. A transmission electron microsco...

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Bibliographic Details
Main Authors: Xinwei Zhao, Xufeng Tao, Lina Xu, Lianhong Yin, Yan Qi, Youwei Xu, Xu Han, Jinyong Peng
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Molecules
Subjects:
apoptosis
dioscin
DNA damage
ROS
cervical carcinoma
Online Access:http://www.mdpi.com/1420-3049/21/6/730

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http://www.mdpi.com/1420-3049/21/6/730

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