Clickable Radiocomplexes With Trivalent Radiometals for Cancer Theranostics: In vitro and in vivo Studies

Clickable Radiocomplexes With Trivalent Radiometals for Cancer Theranostics: In vitro and in vivo Studies

Pre-targeting approaches based on the inverse-electron-demand Diels-Alder (iEDDA) reaction between strained trans-cyclooctenes (TCO) and electron-deficient tetrazines (Tz) have emerged in recent years as valid alternatives to classic targeted strategies to improve the diagnostic and therapeutic prop...

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Bibliographic Details
Main Authors: Alice D'Onofrio, Francisco Silva, Lurdes Gano, Urszula Karczmarczyk, Renata Mikołajczak, Piotr Garnuszek, António Paulo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
in vivo click-chemistry
radiometals
iEDDA
pre-targeting
theranostics
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.647379/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.647379/full

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