Modelling Coupled Oscillations in the Notch, Wnt, and FGF Signaling Pathways during Somitogenesis: A Comprehensive Mathematical Model

Somite formation in the early stage of vertebrate embryonic development is controlled by a complicated gene network named segmentation clock, which is defined by the periodic expression of genes related to the Notch, Wnt, and the fibroblast growth factor (FGF) pathways. Although in recent years some...

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Bibliographic Details
Main Authors: Hong-yan Wang, Yan-xin Huang, Li-hua Zheng, Yong-li Bao, Lu-guo Sun, Yin Wu, Chun-lei Yu, Zhen-bo Song, Ying Sun, Guan-nan Wang, Zhi-qiang Ma, Yu-xin Li
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Computational Intelligence and Neuroscience
Online Access:http://dx.doi.org/10.1155/2015/387409