Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity.

Knock-Down of the 37kDa/67kDa Laminin Receptor LRP/LR Impedes Telomerase Activity.

Cancer has become a major problem worldwide due to its increasing incidence and mortality rates. Both the 37kDa/67kDa laminin receptor (LRP/LR) and telomerase are overexpressed in cancer cells. LRP/LR enhances the invasiveness of cancer cells thereby promoting metastasis, supporting angiogenesis and...

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Bibliographic Details
Main Authors: Kerrilyn Naidoo, Sibusiso T Malindisa, Tyrone C Otgaar, Martin Bernert, Bianca Da Costa Dias, Eloise Ferreira, Uwe Reusch, Stefan Knackmuss, Melvyn Little, Stefan F T Weiss, Boitelo T Letsolo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4636255?pdf=render

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http://europepmc.org/articles/PMC4636255?pdf=render

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