Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite

Abstract While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity. We recently generated a Plasmodium berghei (PbNK65) parasite that lacks a secreted factor, the...

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Bibliographic Details
Main Authors: Claudia Demarta-Gatsi, Roger Peronet, Leanna Smith, Sabine Thiberge, Robert Ménard, Salaheddine Mécheri
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09684-2

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https://doi.org/10.1038/s41598-017-09684-2

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