O 6-methylguanine DNA methyltransferase and glucose transporter 2 in foregut and hindgut gastrointestinal neuroendocrine neoplasms

Abstract Background Streptozocin (STZ) is used for treating both pancreatic (PanNET) and gastrointestinal (GI-NET) neuroendocrine tumors but its therapeutic efficacy is relatively low in GI-NETs. Therefore, it has become pivotal to select GI-NET patients who could benefit from STZ treatment. STZ is...

Full description

Bibliographic Details
Main Authors: Hirofumi Watanabe, Yuto Yamazaki, Fumiyoshi Fujishima, Komoto Izumi, Masayuki Imamura, Susumu Hijioka, Kazuhiro Toriyama, Yasushi Yatabe, Atsushi Kudo, Fuyuhiko Motoi, Michiaki Unno, Hironobu Sasano
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-020-07579-6