A new perspective on transcriptional system regulation (TSR): towards TSR profiling.

It has been hypothesized that the net expression of a gene is determined by the combined effects of various transcriptional system regulators (TSRs). However, characterizing the complexity of regulation of the transcriptome is a major challenge. Principal component analysis on 17,550 heterogeneous h...

Full description

Bibliographic Details
Main Authors: Rudolf S N Fehrmann, Hendrik J M de Jonge, Arja Ter Elst, André de Vries, Anne G P Crijns, Alida C Weidenaar, Frans Gerbens, Steven de Jong, Ate G J van der Zee, Elisabeth G E de Vries, Willem A Kamps, Robert M W Hofstra, Gerard J Te Meerman, Eveline S J M de Bont
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18297136/pdf/?tool=EBI