Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model

Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model

To reveal the pathomechanisms of glaucoma, a common cause of blindness, suitable animal models are needed. As previously shown, retinal ganglion cell and optic nerve degeneration occur in βB1-CTGF mice. Here, we aimed to determine possible apoptotic mechanisms and degeneration of different retinal c...

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Bibliographic Details
Main Authors: Maximilian Weiss, Sabrina Reinehr, Ana M. Mueller-Buehl, Johanna D. Doerner, Rudolf Fuchshofer, Gesa Stute, H. Burkhard Dick, Stephanie C. Joachim
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
βB1-CTGF
primary open-angle glaucoma
apoptosis
caspase 3
neurofilament H
Bax/Bcl2
Online Access:https://www.mdpi.com/1422-0067/22/4/1997

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https://www.mdpi.com/1422-0067/22/4/1997

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