Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats

AIM: To evaluate effect of hypertension on retinal ganglion cell (RGC) apoptosis, intraocular pressure (IOP), and the activation of endothelin-1 (ET-1) signaling pathway in central retinal artery (CRA) in rats. METHODS: The experimental study was performed on 20 male Sprague Dawley rats that were d...

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Bibliographic Details
Main Authors: Seskoati Prayitnaningsih, Hidayat Sujuti, Maksum Effendi, Aulia Abdullah, Nanda Wahyu Anandita, Febriani Yohana, Nur Permatasari, Mohamad Aris Widodo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2016-11-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2016/11/20161106.pdf