Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis

Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis

Abstract Background Ankylosing spondylitis (AS) is characterised by immune-mediated arthritis and osteoproliferation, ultimately leading to joint ankylosis. Whether inflammation is necessary for osteoproliferation is controversial, fuelled by the unclear efficacy of anti-inflammatory treatments on r...

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Bibliographic Details
Main Authors: Hsu-Wen Tseng, Tibor T. Glant, Matthew A. Brown, Tony J. Kenna, Gethin P. Thomas, Allison R. Pettit
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Ankylosing spondylitis
Spondyloarthropathy
Osteoproliferation
Early intervention
Proteoglycan-induced spondylitis mouse model
Online Access:http://link.springer.com/article/10.1186/s12891-017-1600-7

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http://link.springer.com/article/10.1186/s12891-017-1600-7

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