Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish

Perilipin (PLIN) proteins constitute an ancient family important in lipid droplet (LD) formation and triglyceride metabolism. We identified an additional PLIN clade (plin6) that is unique to teleosts and can be traced to the two whole genome duplications that occurred early in vertebrate evolution....

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Bibliographic Details
Main Authors: James G Granneman, Vickie A Kimler, Huamei Zhang, Xiangqun Ye, Xixia Luo, John H Postlethwait, Ryan Thummel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/21771