Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome

Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome

Rett syndrome (RTT) is a rare neurodevelopmental disorder, characterized by severe behavioral and physiological symptoms. Mutations in the methyl CpG binding protein 2 gene (MECP2) cause more than 95% of classic cases, and currently there is no cure for this devastating disorder. Recently we have de...

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Bibliographic Details
Main Authors: Bianca eDe Filippis, Valentina eChiodi, Walter eAdriani, Enza eLacivita, Cinzia eMallozzi, Marcello eLeopoldo, Maria Rosaria eDomenici, Andrea eFuso, Giovanni eLaviola
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Cognition
Intellectual Disability
Serotonin
synaptic plasticity
Transgenic mice
Neurodevelopmental disorders
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00086/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00086/full

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