Cerebral Microbleeds, Cerebrospinal Fluid, and Neuroimaging Markers in Clinical Subtypes of Alzheimer's Disease

Cerebral Microbleeds, Cerebrospinal Fluid, and Neuroimaging Markers in Clinical Subtypes of Alzheimer's Disease

Lobar cerebral microbleeds (CMBs) in Alzheimer's disease (AD) are associated with cerebral amyloid angiopathy (CAA) due to vascular amyloid beta (Aβ) deposits. However, the relationship between lobar CMBs and clinical subtypes of AD remains unknown. Here, we enrolled patients with early- and la...

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Bibliographic Details
Main Authors: Masaki Ikeda, Sayaka Kodaira, Hiroo Kasahara, Eriko Takai, Kazuaki Nagashima, Yukio Fujita, Kouki Makioka, Kimitoshi Hirayanagi, Natsumi Furuta, Minori Furuta, Etsuko Sanada, Ayumi Kobayashi, Yasuo Harigaya, Shun Nagamine, Noriaki Hattori, Yuichi Tashiro, Kazuhiro Kishi, Hirotaka Shimada, Takayuki Suto, Hisashi Tanaka, Yasujiro Sakai, Tsuneo Yamazaki, Yukiko Tanaka, Yuko Aihara, Masakuni Amari, Haruyasu Yamaguchi, Koichi Okamoto, Masamitsu Takatama, Kenji Ishii, Tetsuya Higuchi, Yoshito Tsushima, Yoshio Ikeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neurology
Subjects:
Alzheimer's disease
cerebral microbleeds
posterior cortical atrophy
CSF biomarkers
99mTc ECD-SPECT
11C PiB-PET
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.543866/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.543866/full

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