MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cells

MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cells

Abstract Background Cleft palate (CP) is the second most common congenital birth defect; however, the relationship between CP-associated genes and epigenetic regulation remains largely unknown. In this study, we investigated the contribution of microRNAs (miRNAs) to cell proliferation and regulation...

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Bibliographic Details
Main Authors: Akiko Suzuki, Aimin Li, Mona Gajera, Nada Abdallah, Musi Zhang, Zhongming Zhao, Junichi Iwata
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Medical Genomics
Subjects:
Cleft palate
Bioinformatics
Gene mutation
microRNA
KEGG pathway
Gene ontology
Online Access:http://link.springer.com/article/10.1186/s12920-019-0546-z

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http://link.springer.com/article/10.1186/s12920-019-0546-z

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