miR‐29 contributes to normal endothelial function and can restore it in cardiometabolic disorders

miR‐29 contributes to normal endothelial function and can restore it in cardiometabolic disorders

Abstract We investigated the role of microRNAs (miRNA) in endothelial dysfunction in the setting of cardiometabolic disorders represented by type 2 diabetes mellitus (T2DM). miR‐29 was dysregulated in resistance arterioles obtained by biopsy in T2DM patients. Intraluminal delivery of miR‐29a‐3p or m...

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Bibliographic Details
Main Authors: Michael E Widlansky, David M Jensen, Jingli Wang, Yong Liu, Aron M Geurts, Alison J Kriegel, Pengyuan Liu, Rong Ying, Guangyuan Zhang, Marc Casati, Chen Chu, Mobin Malik, Amberly Branum, Michael J Tanner, Sudhi Tyagi, Kristie Usa, Mingyu Liang
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:EMBO Molecular Medicine
Subjects:
diabetes
endothelium
hypertension
microRNA
nitric oxide
Online Access:https://doi.org/10.15252/emmm.201708046

Internet

https://doi.org/10.15252/emmm.201708046

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