Fiber-specific white matter reductions in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by the loss of both upper and lower motor neurons. Studies using metrics derived from the diffusion tensor model have documented decreased fractional anisotropy (FA) and increased mean diffusivity in the co...

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Bibliographic Details
Main Authors: Luqi Cheng, Xie Tang, Chunxia Luo, Daihong Liu, Yuanchao Zhang, Jiuquan Zhang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303533