Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria

Brain swelling is independent of peripheral plasma cytokine levels in Malawian children with cerebral malaria

Abstract Background Cerebral malaria (CM) is often fatal, and severe brain swelling is a predictor of CM-related mortality. CM is characterized by elevated circulating pro-inflammatory cytokines TNF and IFN-γ and anti-inflammatory cytokine IL-10, however whether cytokine levels correlate with brain...

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Bibliographic Details
Main Authors: Visopo Harawa, Madi Njie, Anne Kessler, Augustine Choko, Benjamin Kumwenda, Sam Kampondeni, Michael Potchen, Kami Kim, Anthony Jaworowski, Terrie Taylor, Wilson Mandala, Karl Seydel, Stephen Rogerson
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Malaria Journal
Subjects:
Cerebral malaria
Brain swelling
Cytokines
Plasmodium falciparum
Africa
Online Access:http://link.springer.com/article/10.1186/s12936-018-2590-0

Internet

http://link.springer.com/article/10.1186/s12936-018-2590-0

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