Expression profiles reveal parallel evolution of epistatic interactions involving the CRP regulon in Escherichia coli.
The extent and nature of epistatic interactions between mutations are issues of fundamental importance in evolutionary biology. However, they are difficult to study and their influence on adaptation remains poorly understood. Here, we use a systems-level approach to examine epistatic interactions th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2242816?pdf=render |