Impaired Memory and Evidence of Histopathology in CA1 Pyramidal Neurons through Injection of Aβ1-42 Peptides into the Frontal Cortices of Rat

Impaired Memory and Evidence of Histopathology in CA1 Pyramidal Neurons through Injection of Aβ1-42 Peptides into the Frontal Cortices of Rat

Introduction: Alzheimer’s disease (AD) is one of the most common neurodegenerative disorders, which has much benefited from animal models to find the basics of its pathophysiology. In our previous work (Haghani, Shabani, Javan, Motamedi, & Janahmadi, 2012), a non-transgenic rat model of AD was u...

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Bibliographic Details
Main Authors: Mohammad Javad Eslamizade, Zahra Madjd, Homa Rasoolijazi, Fatemeh Saffarzadeh, Vahid Pirhajati, Hadi Aligholi, Mahyar Janahmadi, Mehdi Mehdizadeh
Format: Article
Language:English
Published: Iran University of Medical Sciences 2016-01-01
Series:Basic and Clinical Neuroscience
Subjects:
Amyloid-β
Frontal cortex
Hippocampus
Memory
Melatonin
Animal model
Online Access:http://bcn.iums.ac.ir/browse.php?a_code=A-10-473-1&slc_lang=en&sid=1

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http://bcn.iums.ac.ir/browse.php?a_code=A-10-473-1&slc_lang=en&sid=1

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