Evading the host response: Staphylococcus “hiding” in cortical bone canalicular system causes increased bacterial burden

Abstract Extremity reconstruction surgery is increasingly performed rather than amputation for patients with large-segment pathologic bone loss. Debate persists as to the optimal void filler for this “limb salvage” surgery, whether metal or allograft bone. Clinicians focus on optimizing important fu...

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Bibliographic Details
Main Authors: Stephen D. Zoller, Vishal Hegde, Zachary D. C. Burke, Howard Y. Park, Chad R. Ishmael, Gideon W. Blumstein, William Sheppard, Christopher Hamad, Amanda H. Loftin, Daniel O. Johansen, Ryan A. Smith, Marina M. Sprague, Kellyn R. Hori, Samuel J. Clarkson, Rachel Borthwell, Scott I. Simon, Jeff F. Miller, Scott D. Nelson, Nicholas M. Bernthal
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-020-00118-w