Myeloid Clonal Infiltrate Identified With Next-Generation Sequencing in Skin Lesions Associated With Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: A Case Series

Myeloid Clonal Infiltrate Identified With Next-Generation Sequencing in Skin Lesions Associated With Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia: A Case Series

BackgroundMyelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) are associated with cutaneous manifestations. Next-generation sequencing (NGS) is a tool capable of identifying clonal myeloid cells in the skin infiltrate and thus better characterize the link between hematological...

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Bibliographic Details
Main Authors: Grégoire Martin de Frémont, Pierre Hirsch, Santiago Gimenez de Mestral, Philippe Moguelet, Yoan Ditchi, Jean-François Emile, Patricia Senet, Sophie Georgin-Lavialle, Thomas Hanslik, François Maurier, Amir Adedjouma, Noémie Abisror, Thibault Mahevas, Florent Malard, Lionel Adès, Pierre Fenaux, Olivier Fain, François Chasset, Arsène Mekinian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
myelodysplastic syndrome
chronic myelomonocytic leukemia
skin
next-generation sequencing
clonal hematopoiesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715053/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.715053/full

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