Characterizing tyrosine phosphorylation signaling in lung cancer using SH2 profiling.

Tyrosine kinases drive the proliferation and survival of many human cancers. Thus profiling the global state of tyrosine phosphorylation of a tumor is likely to provide a wealth of information that can be used to classify tumors for prognosis and prediction. However, the comprehensive analysis of ty...

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Bibliographic Details
Main Authors: Kazuya Machida, Steven Eschrich, Jiannong Li, Yun Bai, John Koomen, Bruce J Mayer, Eric B Haura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2957407?pdf=render