Multitarget Molecular Hybrids of Cinnamic Acids

Multitarget Molecular Hybrids of Cinnamic Acids

In an attempt to synthesize potential new multitarget agents, 11 novel hybrids incorporating cinnamic acids and paracetamol, 4-/7-hydroxycoumarin, benzocaine, p-aminophenol and m-aminophenol were synthesized. Three hybrids—2e, 2a, 2g—and 3b were found to be multifunctional agents. The hybrid 2e der...

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Bibliographic Details
Main Authors: Aikaterini Peperidou, Dorothea Kapoukranidou, Christos Kontogiorgis, Dimitra Hadjipavlou-Litina
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Molecules
Subjects:
hybrids
cinnamic acids
multitarget
lipoxygenase inhibitors
antiproteolytic activity
analgesics
anti-inflammatories
Online Access:http://www.mdpi.com/1420-3049/19/12/20197

Internet

http://www.mdpi.com/1420-3049/19/12/20197

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