Synthesis and In Vitro Anticancer Evaluation of Novel Chrysin and 7-Aminochrysin Derivatives

Synthesis and In Vitro Anticancer Evaluation of Novel Chrysin and 7-Aminochrysin Derivatives

Chrysin is a naturally occurring flavonoid with mild anticancer activity. In this paper we report the synthesis of new chrysin derivatives alkylated with <i>N</i>-phenylchloroacetamides in position 7. A novel method was developed for the preparation of 7-aminochrysin derivatives via the...

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Bibliographic Details
Main Authors: Szabolcs Mayer, Péter Keglevich, Péter Ábrányi-Balogh, Áron Szigetvári, Miklós Dékány, Csaba Szántay, László Hazai
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
flavonoid
chrysin
aminoflavonoid
anticancer activity
smiles rearrangement
Online Access:https://www.mdpi.com/1420-3049/25/4/888

Internet

https://www.mdpi.com/1420-3049/25/4/888

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