GRP78 Overexpression Triggers PINK1-IP<sub>3</sub>R-Mediated Neuroprotective Mitophagy

GRP78 Overexpression Triggers PINK1-IP<sub>3</sub>R-Mediated Neuroprotective Mitophagy

An experimental model of spinal root avulsion (RA) is useful to study causal molecular programs that drive retrograde neurodegeneration after neuron-target disconnection. This neurodegenerative process shares common characteristics with neuronal disease-related processes such as the presence of endo...

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Bibliographic Details
Main Authors: Tatiana Leiva-Rodríguez, David Romeo-Guitart, Mireia Herrando-Grabulosa, Pau Muñoz-Guardiola, Miriam Polo, Celia Bañuls, Valerie Petegnief, Assumpció Bosch, Jose Miguel Lizcano, Nadezda Apostolova, Joaquim Forés, Caty Casas
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
GRP78/BiP
mitophagy
motoneurons
neurodegeneration
neuroprotection
Online Access:https://www.mdpi.com/2227-9059/9/8/1039

Internet

https://www.mdpi.com/2227-9059/9/8/1039

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