Silencing of G0/G1 switch gene 2 in cutaneous squamous cell carcinoma.

Methylation of a CpG island (CGI; a dense cluster of CpGs) located in the 5' region of a gene suppresses that gene's transcription. The expression of G0/G1 switch gene 2 (G0S2) is potentially associated with tumorigenesis. The aim of this study is to elucidate the methylation status of the...

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Bibliographic Details
Main Authors: Yoshimasa Nobeyama, Yoshinori Watanabe, Hidemi Nakagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5658152?pdf=render